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Pingping Liu,Jia Lv,Cen Ma,Tianqi Zhang,Xiaowen Huang,Zhihui Yang,Lingling Zhang,Jingjie Hu,Shi Wang,Zhenmin Bao,
《工程(英文)》 2022年 第18卷 第11期 页码 259-259 doi: 10.1016/j.eng.2022.09.002
关键词: online THE AUTHORS.Published repertoire behalf Engineering September genotyping Academy HD-marker approach” Education Press Limited Company.
Transcriptome resources and genome-wide marker development for Japanese larch (
Wanfeng LI,Suying HAN,Liwang QI,Shougong ZHANG
《农业科学与工程前沿(英文)》 2014年 第1卷 第1期 页码 77-84 doi: 10.15302/J-FASE-2014010
关键词: Larix transcriptome age wood formation somatic embryogenesis molecular marker
智能城市(iCity) 中自动驾驶汽车工业的关键挑战——高清地图 Perspective
Heiko G. Seif,胡晓龙
《工程(英文)》 2016年 第2卷 第2期 页码 159-162 doi: 10.1016/J.ENG.2016.02.010
本文对未来城市中自动驾驶的必要技术进行了深入的分析,从车载电脑运算、数据处理、路边基础设施和云解决方案等不同方面反映了科技的发展状况,主要对自动驾驶的核心技术——高清地图的应用所带来的挑战进行了描述。
Chinmedomics facilitated quality-marker discovery of Sijunzi decoction to treat spleen qi deficiency
Qiqi Zhao, Xin Gao, Guangli Yan, Aihua Zhang, Hui Sun, Ying Han, Wenxiu Li, Liang Liu, Xijun Wang
《医学前沿(英文)》 2020年 第14卷 第3期 页码 335-356 doi: 10.1007/s11684-019-0705-9
关键词: traditional Chinese medicine Sijunzi decoction spleen qi deficiency syndrome Chinmedomics quality-marker
null
《医学前沿(英文)》 2016年 第10卷 第1期 页码 52-60 doi: 10.1007/s11684-016-0433-3
Hepatocellular carcinoma (HCC) is a lethal liver malignancy worldwide. In this study, we reported that protein phosphatase magnesium-dependent 1δ (PPM1D) was highly expressed in the majority of HCC cases (approximately 59%) and significantly associated with high serum α-fetoprotein (AFP) level (P= 0.044). Kaplan-Meier and Cox regression data indicated that PPM1D overexpression was an independent predictor of HCC-specific overall survival (HR, 2.799; 95% CI, 1.346–5.818, P = 0.006). Overexpressing PPM1D promoted cell viability and invasion, whereas RNA interference-mediated knockdown of PPM1D inhibited proliferation, invasion, and migration of cultured HCC cells. In addition, PPM1D suppression by small interfering RNA decreased the tumorigenicity of HCC cells in vivo. Overall, results suggest that PPM1D is a potential prognostic marker and therapeutic target for HCC.
关键词: PPM1D hepatocellular carcinoma prognosis target therapy
Novel polymorphic EST-based microsatellite marker isolation and characterization from
Manosh Kumar BISWAS,Peng CHEN,Mohamed Hamdy AMAR,Xiuxin DENG
《农业科学与工程前沿(英文)》 2015年 第2卷 第1期 页码 60-65 doi: 10.15302/J-FASE-2015048
Caiyun LIU, Francisco PINTO, C. Mariano COSSANI, Sivakumar SUKUMARAN, Matthew P. REYNOLDS
《农业科学与工程前沿(英文)》 2019年 第6卷 第3期 页码 296-308 doi: 10.15302/J-FASE-2019269
The application of spectral reflectance indices (SRIs) as proxies to screen for yield potential (YP) and heat stress (HS) is emerging in crop breeding programs. Thus, a comparison of SRIs and their associations with grain yield (GY) under YP and HS conditions is important. In this study, we assessed the usefulness of 27 SRIs for indirect selection for agronomic traits by evaluating an elite spring wheat association mapping initiative (WAMI) population comprising 287 elite lines under YP and HS conditions. Genetic and phenotypic analysis identified 11 and 9 SRIs in different developmental stages as efficient indirect selection indices for yield in YP and HS conditions, respectively. We identified enhanced vegetation index (EVI) as the common SRI associated with GY under YP at booting, heading and late heading stages, whereas photochemical reflectance index (PRI) and normalized difference vegetation index (NDVI) were the common SRIs under booting and heading stages in HS. Genome-wide association study (GWAS) using 18704 single nucleotide polymorphisms (SNPs) from Illumina iSelect 90K identified 280 and 43 marker-trait associations for efficient SRIs at different developmental stages under YP and HS, respectively. Common genomic regions for multiple SRIs were identified in 14 regions in 9 chromosomes: 1B (60–62 cM), 3A (15, 85–90, 101–105 cM), 3B (132–134 cM), 4A (47–51 cM), 4B (71–75 cM), 5A (43–49, 56–60, 89–93 cM), 5B (124–125 cM), 6A (80–85 cM), and 6B (57–59, 71 cM). Among them, SNPs in chromosome 5A (89–93 cM) and 6A (80–85 cM) were co-located for yield and yield related traits. Overall, this study highlights the utility of SRIs as proxies for GY under YP and HS. High heritability estimates and identification of marker-trait associations indicate that SRIs are useful tools for understanding the genetic basis of agronomic and physiological traits.
关键词: genome-wide association study (GWAS) heat tolerance spectral reflectance spring wheat
TRANSLATING THE MULTI-ACTOR APPROACH TO RESEARCH INTO PRACTICE USING A WORKSHOP APPROACH FOCUSING ON
《农业科学与工程前沿(英文)》 2021年 第8卷 第3期 页码 460-473 doi: 10.15302/J-FASE-2021416
The EIP-Agri multiactor approach was exemplified during a 3-day workshop with 63 project participants from the EU H2020 funded project “Redesigning European cropping systems based on species MIXtures”. The objective was to share firsthand experience of participatory research among researchers who were mostly not familiar with this approach. Workshop participants were divided into smaller multidisciplinary groups and given the opportunity to interact with representatives from eight actor positions in the value chain of the agrifood cooperative Terrena located in Western France. The four stages of the workshop were: (1) key actor interviews, (2) sharing proposed solutions for overcoming barriers, and (3) developing possible interdisciplinary concepts. Expressions of frustration were recorded serving both as a motivation for group members to become more aware of the scientific concerns and practices of their colleagues, as well as a recognition that some researchers have better skills integrating qualitative approaches than others. Nevertheless, the workshop format was an effective way to gain a common understanding of the pertinent issues that need to be addressed to meet overall multiactor-approach objectives. Working with the actor networks was identified and emphasized as a means to overcome existing barriers between academia and practice in order to coproduce a shared vision of the benefits of species mixture benefits.
关键词: agroecology codesign intercropping knowledge sharing participatory methods
《农业科学与工程前沿(英文)》 2021年 第8卷 第2期
Seedless fruits are desirable in the citrus fresh fruit market. Triploid production via diploid × tetraploid interploidy crosses is thought to be the most efficient and widely-used strategy for the breeding of seedless citrus. Although ‘Orah’ mandarin has desirable organoleptic qualities, seeds in the fruits weaken its market competitiveness. To produce new seedless cultivars that are similar to ‘Orah’ mandarin, we performed three 2x × 4x crosses using ‘Orah’ mandarin as the seed parent to regenerate triploid plantlets. A total of 182 triploid and 36 tetraploid plantlets were obtained. By analyzing their genetic origins using nine novel single nucleotide polymorphism (SNP) markers, all of the triploids and tetraploids derived from these three crosses were proven to be hybrids. Also, we demonstrated that 2n megagametophyte formation in ‘Orah’ mandarin result in tetraploid production in these three interploidy crosses. These tetraploid plantlets were genotyped using eight pericentromeric SNP markers and nine centromere distal SNP markers. Based on the genotypes of the 2n megagametophytes, the parental heterozygosity rates in 16 SNP loci and all 2n megagametophytes were less than 50%, indicating that second division restitution was the mechanism underlying 2n megagametophyte formation at both the population and individual levels. These triploid hybrids enrich the germplasm available for seedless breeding. Moreover, the tetraploid hybrids are valuable as parents for ploidy breeding for the production of seedless citrus fruits.
Governance approach to China’s environmental challenges: Towards a theoretical synthesis
QI Ye, XUE Lan, ZHANG Lingyun
《环境科学与工程前沿(英文)》 2007年 第1卷 第4期 页码 385-400 doi: 10.1007/s11783-007-0066-5
关键词: environmental governance approach temporal regulation various
Comparison of surgical indications for hysterectomy by age and approach in 4653 Chinese women
null
《医学前沿(英文)》 2014年 第8卷 第4期 页码 464-470 doi: 10.1007/s11684-014-0338-y
Approximately one million hysterectomies are performed each year in China. However, national data regarding the indications and the surgical approaches for hysterectomy are lacking. The aim of this study was to examine the surgical indications for hysterectomy in different age groups and the relative merits of different surgical approaches for hysterectomy in Chinese women. Clinical data from 4653 cases of hysterectomy performed in Tongji Hospital from 2004 to 2009 were analysed. Hysterectomy was most commonly performed among women aged 40--49 years (2299; 49.4%). Overall, colporrhagia and abdominal pain were the two most common indications for hysterectomy. The most common indications by age groups were as follows: malignant ovarian tumour,<20 years; malignant uterine tumour, 20--29 and 30--39 years; uterine myoma, 40--49 and 50--59 years; and uterine prolapse, 60--69 and>70 years. The proportion of malignant aetiology also varied by age, being the highest in women aged<20 years (75.0%) and the lowest in those aged 40--49 years (19.9%). Approximately 35% women who had hysterectomies also had concomitant bilateral oophorectomy. The lowest rate of oophorectomy occurred in women aged 30--39 years (15.8%), whereas the highest rate was in those aged 50--59 years (75.9%). The abdominal surgical approach was used in 84% of all hysterectomies. Surgeries using the vaginal approach required a significantly shorter operating time (118 min average) than all other approaches (P<0.05). Both the amount of bleeding and the blood transfusion volume required were smaller in vaginal approaches, with no significant differences between the others. The surgical approaches used were also related to the scope of surgery. Both the surgical indications and the rates of bilateral oophorectomy varied by age. In terms of both operating time and the amount of bleeding and blood transfusion volume required, the vaginal approach was superior to all other surgical approaches.
关键词: hysterectomy surgical indications surgical approach bilateral oophorectomy
Hierarchical approach for fatigue cracking performance evaluation in asphalt pavements
Ibrahim ONIFADE, Yared DINEGDAE, Björn BIRGISSON
《结构与土木工程前沿(英文)》 2017年 第11卷 第3期 页码 257-269 doi: 10.1007/s11709-017-0410-1
关键词: fatigue cracking energy based crack initiation mechanistic approach pavement analysis
Zhang Harry, Yu Shaw
《环境科学与工程前沿(英文)》 2008年 第2卷 第3期 页码 267-273 doi: 10.1007/s11783-008-0058-0
关键词: representative hydrologic occurrence simulation approach scarcity alternative
Promising approach for preparing metallic single-atom catalysts: electrochemical deposition
《能源前沿(英文)》 2022年 第16卷 第4期 页码 537-541 doi: 10.1007/s11708-022-0837-5
Exploring the diagnosis markers for gallbladder cancer based on clinical data
null
《医学前沿(英文)》 2015年 第9卷 第3期 页码 350-355 doi: 10.1007/s11684-015-0402-2
Presently, no effective markers are available to facilitate gallbladder cancer (GBC) diagnosis. This study aims to explore available markers for GBC diagnosis. Clinical data of 144 GBC and 116 cholelithiasis patients were retrospectively reviewed. Logistic regression analysis was performed to evaluate GBC risk factors. A receiver operating characteristic (ROC) curve was used to assess the diagnosis value of the risk factors. By comparing the characteristic of GBC and cholelithiasis patients, the following factors exhibited statistical difference: age, gender, gallstones, total bilirubin (TB), alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), platelet count (PLT), CA125 (carcinoembryonic antigen 125), and CA199 (carbohydrate antigen 199). Logistic regression analysis indicated that age [odds ratio (OR), 1.032; 95% confidence interval (95% CI), 1.004 to 1.061; P = 0.024], gender (OR, 0.346; 95% CI, 0.167 to 0.716; P = 0.004), gallstones (OR, 0.027; 95% CI, 0.007 to 0.095; P<0.001), ALP (OR, 1.003; 95% CI, 1.000 to 1.006; P = 0.032), TB (OR, 1.004; 95% CI, 1.000 to 1.009; P = 0.042), and CA125 (OR, 1.007; 95% CI, 1.002 to 1.013; P = 0.011) were independent risk factors for GBC. According to the ROC curve, CA125 [area under curve (AUC), 0.720], ALP (AUC, 0.713), TB (AUC, 0.636), and age (AUC, 0.573) were valuable diagnosis markers. Additionally, based on the independent risk factors, the GBC diagnosis model was established. Age, TB, ALP, and CA125 can be used as auxiliary diagnosis factors of GBC. The diagnosis model provides a quantitative tool for GBC diagnosis when comprehensively considering various risk factors.
标题 作者 时间 类型 操作
Erratum to “Targeted Genotyping of a Whole-Gene Repertoire by an Ultrahigh-Multiplex and Flexible HD-MarkerApproach” [Engineering 13 (2022) 186–196]
Pingping Liu,Jia Lv,Cen Ma,Tianqi Zhang,Xiaowen Huang,Zhihui Yang,Lingling Zhang,Jingjie Hu,Shi Wang,Zhenmin Bao,
期刊论文
Transcriptome resources and genome-wide marker development for Japanese larch (
Wanfeng LI,Suying HAN,Liwang QI,Shougong ZHANG
期刊论文
Chinmedomics facilitated quality-marker discovery of Sijunzi decoction to treat spleen qi deficiency
Qiqi Zhao, Xin Gao, Guangli Yan, Aihua Zhang, Hui Sun, Ying Han, Wenxiu Li, Liang Liu, Xijun Wang
期刊论文
Protein phosphatase magnesium-dependent 1δ is a novel tumor marker and target in hepatocellular carcinoma
null
期刊论文
Novel polymorphic EST-based microsatellite marker isolation and characterization from
Manosh Kumar BISWAS,Peng CHEN,Mohamed Hamdy AMAR,Xiuxin DENG
期刊论文
as proxies for yield potential and heat stress tolerance in spring wheat: heritability estimates and marker-trait
Caiyun LIU, Francisco PINTO, C. Mariano COSSANI, Sivakumar SUKUMARAN, Matthew P. REYNOLDS
期刊论文
TRANSLATING THE MULTI-ACTOR APPROACH TO RESEARCH INTO PRACTICE USING A WORKSHOP APPROACH FOCUSING ON
期刊论文
UNREDUCED MEGAGAMETOPHYTE FORMATION VIA SECOND DIVISION RESTITUTION CONTRIBUTES TO TETRAPLOID PRODUCTION IN INTERPLOIDY CROSSES WITH ‘ORAH’ MANDARIN (CITRUS RETICULATA)
期刊论文
Governance approach to China’s environmental challenges: Towards a theoretical synthesis
QI Ye, XUE Lan, ZHANG Lingyun
期刊论文
Comparison of surgical indications for hysterectomy by age and approach in 4653 Chinese women
null
期刊论文
Hierarchical approach for fatigue cracking performance evaluation in asphalt pavements
Ibrahim ONIFADE, Yared DINEGDAE, Björn BIRGISSON
期刊论文
Critical flow-storm approach to total maximum daily load (TMDL) development: an analytical conceptual
Zhang Harry, Yu Shaw
期刊论文